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PTGXProtagonist Therapeutics, Inc

Options Analysis Report•PHARMACEUTICAL PREPARATIONS
Market Cap $9.3B|NASDAQ
● 2026-08-31$144.33
NEUTRAL
Analysis: 2026-08-28 EOD data
1Y +145.3%YTD +65.6%7D -6.7%
16
30D
±13.3%
11%

PTGX Options Overview

IV is elevated. Conditions favor premium sellers.

REWARDS

RISK ANALYSIS

4.5VALUESENTIMENTACTIVITYLIQUIDITYTIMING

Snowflake Analysis

Favorable conditions for premium sellers

Learn
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PTGX Gamma Walls

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Value

Is IV priced right?

7.0
ExpensiveCheap

Measures whether options are cheap, fair, or rich relative to historical and peer

levels.

Risk Checks6/9 checks passed
≤35%

IV Rank 71.3% — elevated vs history

<1.05x

IV/HV 1.14x — IV premium over HV

Sector Relative≤50%

Sector percentile 41% — below sector median

<1.1x

Front/Back 1.07x — backwardation

<1.25x

Put/Call IV 1.16x — elevated

<80%

ATM IV 45.7% — normal range

<80%

Effective IV 79.9% (ATM 45.7% + spread 17.1% + bias) — fair

<3.0%

Total drag 24.57% (spread 17.11% + slippage 7.46%) — high friction

≥5.0

Vega efficiency 20.56 (vega 35.171 / spread 17.11%) — efficient

Sentiment

Bullish or bearish?

4.9
BearishBullish

Analyzes

,
, and flow direction to determine market bias.

Risk ChecksBearish - Moderate signal (Conviction: -19%, Raw: -25%)
|net sentiment| ≥25%

Conviction-weighted: -19% (bearish) — Raw: -25%

≥15%

|OI skew| 45.0% — call-heavy

Same sign, |vol skew| ≥10%

Vol skew +0.0%, OI skew +45.0% — divergent (opposite)

≥2/3 conditions

0-DTE 0%, far-OTM 15%, avg DTE 30

|change| ≥3%

OI change +0.0% (5d) — stable

|weighted flow| ≥20%

ITM: -100%, ATM: +100%, OTM: -80% — bearish (ITM/ATM divergent)

Sector Relative≤40% or ≥60%

Sector P/C percentile 58% — bearish vs sector

Activity

Unusual activity?

1.8
QuietActive

Detects volume surges,

, and unusual options activity that may signal moves.

Risk Checks0/8 checks passed
≥1.5x

Volume 0.1x avg — normal

≥15%

Vol/OI 0.2% — normal turnover

≥2 days

1 day(s) elevated — may be one-day event

≥5%

OI change +1.9% (5d) — stable

Sector Relative≥60%

Sector activity percentile 12% — quiet vs sector

≥30%

Large trade volume 0% — mostly retail

≥60%

Aggressive execution 29% — patient

≥30

Conviction -19 (bearish) — mixed

Liquidity

Can I trade efficiently?

2.1
IlliquidLiquid

Evaluates

, volume depth, and open interest for trade execution quality.

Risk Checks0/8 checks passed
≤5.0%

Spread 17.1% — wide

≥10,000

OI 6,421 — thin

≥500

Volume 16/day — thin

≤$0.50

$0.86 to cross — expensive

≥5 strikes

0 liquid strikes — limited options

Sector Relative≤40%

Sector spread percentile 75% — wider than sector

≥100 contracts

Depth 14.7 contracts (bid:6.3 ask:8.4) — thin

<1.0%

Avg slippage 7.46% — poor

Timing

Is now a good time?

6.8
RiskyFavorable

Considers earnings proximity,

, and event calendar for optimal entry timing.

Risk Checks6/9 checks passed
|slope| ≥5%

Slope +6.9% — backwardation

<30 or >70

IV percentile 71% — seller opportunity

≥10pts kink

IV kink 0.0pts — no clear event

<0.5 or >2.0

θ/ν ratio 559.15 — favors income trades

≥3 expirations

3 liquid expirations — flexible

≥60% (safe)

safe window: No events detected

<1.2 ratio

Spread ratio 1.00x — stable

≥25% strength + ≥50% consistency

Flow -19% @ 62% consistency — unclear

≥40 composite score

Score 30 (ITM 20% + inst 0%) — retail dominated

Directional Strategy Fit

Option Buyers
Long Calls5.5
bullishIV cheap, mixed flow
Long Puts5.6
bearishIV cheap, mixed flow
Premium Sellers
Cash-Secured Put4.0
bullishIV too cheap, mixed flow
Covered Call4.1
bearishIV too cheap, mixed flow

For educational purposes only. Not investment advice.

The Options Desk tracks the move options price into every US earnings report the week of Aug 31, next to how much each stock has actually moved on its past prints — plus the SPY, QQQ and IWM expected ranges and the gamma walls that box them in.

More on PTGX

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