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DNLIDenali Therapeutics Inc. Common Stock

Options Analysis Report•BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
Market Cap $3.8B|NASDAQ
● 2026-08-31$24.00
BEARISH
Analysis: 2026-08-28 EOD data
1Y +55.3%YTD +47.5%7D -0.8%
1,765
30D
±8.6%
7%

DNLI Options Overview

bearish flow with unusual activity. No clear edge detected.

REWARDS

RISK ANALYSIS

5.1VALUESENTIMENTACTIVITYLIQUIDITYTIMING

Snowflake Analysis

Balanced conditions with no clear edge

Learn
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DNLI Gamma Walls

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Value

Is IV priced right?

7.0
ExpensiveCheap

Measures whether options are cheap, fair, or rich relative to historical and peer

levels.

Risk Checks6/9 checks passed
≤35%

IV Rank 50.0% — elevated vs history

<1.05x

IV/HV 1.00x — IV ≤ HV

Sector Relative≤50%

Sector percentile 50% — below sector median

<1.1x

Front/Back 1.00x — flat

<1.25x

Put/Call IV 1.00x — normal

<80%

ATM IV 0.0% — normal range

<80%

Effective IV 25.8% (ATM 0.0% + spread 12.9% + bias) — excellent value

<3.0%

Total drag 15.35% (spread 12.88% + slippage 2.47%) — high friction

≥5.0

Vega efficiency 0.00 (vega 0.000 / spread 12.88%) — spread drag

Sentiment

Bullish or bearish?

3.1
BearishBullish

Analyzes

,
, and flow direction to determine market bias.

Risk ChecksBearish - Strong signal (Conviction: -11%, Raw: -12%)
|net sentiment| ≥25%

Conviction-weighted: -11% (bearish) — Raw: -12%

≥15%

|OI skew| 27.3% — put-heavy

Same sign, |vol skew| ≥10%

Vol skew -29.3%, OI skew -27.3% — aligned

≥2/3 conditions

0-DTE 0%, far-OTM 15%, avg DTE 30

|change| ≥3%

OI change +0.0% (5d) — stable

|weighted flow| ≥20%

ITM: -11%, ATM: -5%, OTM: -30% — neutral (ITM/ATM aligned)

Sector Relative≤40% or ≥60%

Sector P/C percentile 83% — very bearish vs sector

Activity

Unusual activity?

6.2
QuietActive

Detects volume surges,

, and unusual options activity that may signal moves.

Risk Checks5/8 checks passed
≥1.5x

Volume 1.9x avg — elevated

≥15%

Vol/OI 15.5% — high turnover

≥2 days

4 day(s) elevated — sustained

≥5%

OI change +7.3% (5d) — building

Sector Relative≥60%

Sector activity percentile 95% — very active vs sector

≥30%

Large trade volume 0% — mostly retail

≥60%

Aggressive execution 2% — patient

≥30

Conviction -11 (bearish) — mixed

Liquidity

Can I trade efficiently?

3.7
IlliquidLiquid

Evaluates

, volume depth, and open interest for trade execution quality.

Risk Checks3/8 checks passed
≤5.0%

Spread 12.9% — wide

≥10,000

OI 11,374 — adequate

≥500

Volume 1,765/day — adequate

≤$0.50

$0.64 to cross — expensive

≥5 strikes

0 liquid strikes — limited options

Sector Relative≤40%

Sector spread percentile 0% — much tighter than sector

≥100 contracts

Depth 79.1 contracts (bid:41.4 ask:37.7) — thin

<1.0%

Avg slippage 2.47% — poor

Timing

Is now a good time?

5.5
RiskyFavorable

Considers earnings proximity,

, and event calendar for optimal entry timing.

Risk Checks3/9 checks passed
|slope| ≥5%

Slope +0.0% — flat/unclear

<30 or >70

IV percentile 50% — neutral

≥10pts kink

IV kink 0.0pts — no clear event

<0.5 or >2.0

θ/ν ratio 1.00 — favors mixed

≥3 expirations

3 liquid expirations — flexible

≥60% (safe)

safe window: No events detected

<1.2 ratio

Spread ratio 1.00x — stable

≥25% strength + ≥50% consistency

Flow -11% @ 55% consistency — unclear

≥40 composite score

Score 30 (ITM 20% + inst 0%) — retail dominated

Directional Strategy Fit

Option Buyers
Long Calls4.9
bullishIV cheap, bearish flow
Long Puts7.0
bearishIV cheap, bearish flow
Premium Sellers
Cash-Secured Put3.6
bullishIV too cheap, bearish flow
Covered Call4.9
bearishIV too cheap, bearish flow

For educational purposes only. Not investment advice.

The Options Desk tracks the move options price into every US earnings report the week of Aug 31, next to how much each stock has actually moved on its past prints — plus the SPY, QQQ and IWM expected ranges and the gamma walls that box them in.

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