Options/MDGL

MDGLMadrigal Pharmaceuticals, Inc. Common Stock

Options Analysis Report•PHARMACEUTICAL PREPARATIONS

Market Cap $12.3B|NASDAQ

● 2026-09-11$533.12

NEUTRAL

Analysis: 2026-09-10 EOD data

1Y +21.3%YTD -10.2%7D -1.5%

Options Vol

105

30D

Implied Move

±8.6%

IV Rank

32%

MDGL Options Overview

IV is elevated. Conditions favor premium sellers.

REWARDS

RISK ANALYSIS

Snowflake Analysis

Favorable conditions for premium sellers

Learn

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MDGL Gamma Walls

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Value

Is IV priced right?

5.8

ExpensiveCheap

Measures whether options are cheap, fair, or rich relative to historical and peer

levels.

Risk Checks6/9 checks passed

IV Rank

≤35%

IV Rank 72.7% — elevated vs history

IV/HV Ratio

<1.05x

IV/HV 1.30x — IV premium over HV

Sector Relative≤50%

Sector percentile 47% — below sector median

Term Structure

<1.1x

Front/Back 0.78x — contango

Skew Normal

<1.25x

Put/Call IV 1.16x — elevated

Absolute IV

<80%

ATM IV 50.9% — normal range

Spread-Adjusted Value

<80%

Effective IV 78.8% (ATM 50.9% + spread 14.0% + bias) — fair

Execution Efficiency

<3.0%

Total drag 27.06% (spread 13.96% + slippage 13.10%) — high friction

Vega Efficiency

≥5.0

Vega efficiency 78.77 (vega 109.960 / spread 13.96%) — efficient

Sentiment

Bullish or bearish?

5.2

BearishBullish

Analyzes

put/call ratios

open interest skew

, and flow direction to determine market bias.

Risk ChecksNeutral - Moderate signal (Conviction: +2%, Raw: +11%)

Flow Direction

|net sentiment| ≥25%

Conviction-weighted: +2% (neutral) — Raw: +11%

OI Skew Magnitude

≥15%

|OI skew| 40.8% — call-heavy

Volume-OI Alignment

Same sign, |vol skew| ≥10%

Vol skew -4.8%, OI skew +40.8% — divergent (opposite)

Conviction Quality

≥2/3 conditions

0-DTE 0%, far-OTM 15%, avg DTE 30

OI Momentum

|change| ≥3%

OI change +0.0% (5d) — stable

Smart Money Flow

|weighted flow| ≥20%

ITM: -100%, ATM: +33%, OTM: +14% — strong bearish (ITM/ATM divergent)

Sector Relative≤40% or ≥60%

Sector P/C percentile 79% — very bearish vs sector

Activity

Unusual activity?

1.9

QuietActive

Detects volume surges,

block trades

, and unusual options activity that may signal moves.

Risk Checks0/8 checks passed

Volume Surge

≥1.5x

Volume 0.3x avg — normal

Turnover Rate

≥15%

Vol/OI 0.8% — normal turnover

Multi-Day Persistence

≥2 days

1 day(s) elevated — may be one-day event

OI Build

≥5%

OI change +3.0% (5d) — building

Sector Relative≥60%

Sector activity percentile 36% — below sector avg

Trade Quality

≥30%

Large trade volume 0% — mostly retail

Execution Urgency

≥60%

Aggressive execution 8% — patient

Flow Conviction

≥30

Conviction +2 (bullish) — mixed

Liquidity

Can I trade efficiently?

2.5

IlliquidLiquid

Evaluates

bid-ask spreads

, volume depth, and open interest for trade execution quality.

Risk Checks1/8 checks passed

Tradeable Spread

≤5.0%

Spread 14.0% — wide

Adequate OI

≥10,000

OI 13,136 — adequate

Active Volume

≥500

Volume 105/day — thin

Reasonable Cost

≤$0.50

$0.70 to cross — expensive

Strike Coverage

≥5 strikes

0 liquid strikes — limited options

Sector Relative≤40%

Sector spread percentile 79% — wider than sector

Order Book Depth

≥100 contracts

Depth 12.5 contracts (bid:5.9 ask:6.6) — thin

Execution Quality

<1.0%

Avg slippage 13.10% — poor

Timing

Is now a good time?

6.1

RiskyFavorable

Considers earnings proximity,

time decay

, and event calendar for optimal entry timing.

Risk Checks5/9 checks passed

Term Structure Clarity

|slope| ≥5%

Slope -21.8% — contango

IV Percentile Clarity

<30 or >70

IV percentile 73% — seller opportunity

Event Detection

≥10pts kink

IV kink -6.5pts — no clear event

Theta/Vega Clarity

<0.5 or >2.0

θ/ν ratio 343.84 — favors income trades

Expiration Distribution

≥3 expirations

3 liquid expirations — flexible

Event Risk

≥60% (safe)

caution advised: FOMC in 5d; CPI in 0d (HIGH)

Spread Momentum

<1.2 ratio

Spread ratio 1.00x — stable

Flow Momentum

≥25% strength + ≥50% consistency

Flow +2% @ 51% consistency — unclear

Smart Money Timing

≥40 composite score

Score 30 (ITM 20% + inst 0%) — retail dominated

Directional Strategy Fit

Option Buyers

Long Calls5.2

bullishIV fair, mixed flow

Long Puts5.0

bearishIV fair, mixed flow

Premium Sellers

Cash-Secured Put4.5

bullishIV fair, mixed flow

Covered Call4.3

bearishIV fair, mixed flow

For educational purposes only. Not investment advice.

The Options Desk tracks the move options price into every US earnings report the week of Sep 7, next to how much each stock has actually moved on its past prints — plus the SPY, QQQ and IWM expected ranges and the gamma walls that box them in.

More on MDGL

MDGL gamma walls MDGL option chain MDGL max pain MDGL expected move MDGL IV rank MDGL put/call ratio MDGL options flow